H e proposed, instead, a krukenberga s metastatic ovarian carcinoma. The majority are benign, but some can be malignant they are most frequently found incidentally on pelvic examination or at laparotomy. Krukenberg tumor article about krukenberg tumor by the. Karcinom i aggstockens slemhinneceller, oftast metastaser fran magtarmkanalen, som kannetecknas av slemhinnedefekter och forekomst av signetringsliknande celler. We report a series of 9 patients with krukenberg tumors treated at the casablanca university hospital between 1982 and 1999. Jorge ymaya cirujano oncologo catedra oncologia, uasd. Any information contained in this pdf file is automatically generated from digital material submitted to epos by third parties in the form of scientific presentations. The ultrasound showed a 55 mm solid right ovarian tumor and a 125 mm left cystic ovarian tumor. Gastric adenocarcinoma, especially at the pylorus, is the most common source. They were secondary metastatic involvement from gastric tumors 3 cases, colon 1 case and gallbladder 1 case. A krukenberg tumor refers to a malignancy in the ovary metastasized from a primary site, classically the gastroin. Since the time of krukenberg in 1896, all ovarian tumors which enlarge. Histology shows typical mucusproduction and numerous signetring cells.
Some studies have shown stomach cancer to be primary site in about 70% of krukenberg tumor cases 5. Krukenberg tumor is a rare ovarian metastatic cancer from the gastrointestinal tract. A case of virilization induced by a krukenberg tumor from. They are in most instances bilateral and produce a. The krukenberg tumor represents ovarian metastases associated with gastric cancer or other gastrointestinal malignancies. Krukenburg tumor is a metastatic malignancy of the ovary characterized by mucinrich signetring adenocarcinoma that primarily arises from a. Sep 02, 2015 krukenberg tumor is a rare metastastic tumor of the ovary, characterized by poor prognosis. Gastric and colorectal cancers together account for almost entire 90% of the pr imary site for the origin of this tumor 5 7. Krukenbergs tumor article about krukenbergs tumor by the. The covariates used for survival analysis were patient age at the time of ovarian relapse categorized as 50 years, size of krukenberg s tumor categorized as 10 cm, initial ajcc stage of gastric carcinoma, relapsefree interval categorized as 2 years, extent of recurrent disease, and the.
Diagnosis of the krukenberg tumor since the time of. Clinical characteristics and prognostic analysis of. Bilateral ovarian carcinoma metastatic from the ampulla of vater. Krukenberg tumor is more commonly observed among women in their fifth decade of lives, with an average around 45 years of age. Clinical characteristics and prognostic analysis of krukenberg tumor. This study aims to describe the unusual case of a 36yearold woman that presented to the emergency department ed with back.
Karcinomtypen utgor 3040% av alla aggstocksmetastaser och kanske 12% av alla elakartade aggstockstumorer. The incidence of metastatic tumors of the ovary is very small 15%, and. Krukenberg tumor is defined as a metastatic uni or bilateral ovarian tumor that contains significant amounts of signet ring cells and whose origin is mainly gastrointestinal. Krukenberg tumor presenting as back pain and a positive. Cholangiocarcinoma is a rare tumor of the biliary tract, despite being the second most common primary neoplasm of the liver. Click on the link to view a sample search on this topic. All structured data from the file and property namespaces is available under. This metastasis generally comes from the digestive tube, mainly from.
Transitional cell carcinoma is an even rarer entity, in which neoplastic transitional epithelial cells similar to transitional cell carcinoma of the bladder are seen in the ovary, without the characteristic stromalepithelial pattern of a brenner tumour. About 5% of brenner tumors are cancerous malignant or have a small chance of spreading beyond its original location borderline. Still there is very few literature description r elated to this issue. The colon and stomach are the most common primary tumors to result in ovarian metastases, followed by the breast, lung, and contralateral ovary. Is there anyone female, that is online here with krukenberg tumours from stomach cancer. She came to our institution with a twenty month history of. Krukenberg tumors account for approximately 15% of malignant. General surgery of playa del carmen general hospital, av. All stage iv stomach cancer krukenberg tumours messages.
Pdf an adnexal mass in pregnancy is a malignant tumor in 25% of cases. Since the time of krukenberg in 1896, all ovarian tumors which enlarge the ovaries uniformly without distortion, which present alterations of fibrous areas with mucinouscell groups, and which propagate along the lymphatics are called krukenberg tumors 6. It accounts for 1%5% of malignant tumors of the ovaries, usually being bilateral, of solid consistency and may have cystic areas. Krukenberg tumor is a rare metastastic tumor of the ovary, characterized by poor prognosis. Occasionally krukenberg tumors have endocrine function and, as a consequence, some patients demonstrate hirsutism and virilization. Krukenberg tumor is named after friedrich ernst krukenberg who described five cases of krukenberg tumors in 1896 while working as a student in a laboratory in germany. Despite the limitation in survival time early oopherectomy should be considered to prevent the development of virilization even in palliative situations if a krukenberg tumor is diagnosed with gastric cancer. Brenner tumors are an uncommon subtype of the surface epithelialstromal tumor group of ovarian neoplasms. Krukenberg tumor is a rare metastatic signet ring cell tumor of the ovary, accounting for 12% of all ovarian tumors.
I was diagnosed with stage iv stomach cancer peritoneal metastases almost 15 months ago, had a a partial gastrectomy, 19 months of chemo eox, and felt extremely well since then. The krukenberg tumor is a mysterious ovarian metastasis of digestive tract cancer accounting from 1 to 2% of all ovarian tumors. The reason for so may be the rare incidence of this disease krukenberg tumor which. A krukenberg tumor refers to a malignancy in the ovary that metastasized from a primary site, classically the gastrointestinal tract, although it can arise in other tissues such as the breast. However, even if the cancer has spread, it is still named for the area where it began. Diagnostic problem schiller emphasized that this, also, was a poor choice, because the name was used loosely to include all varieties 01 metastatic carcinoma to the ovary. Krukenbergs tumor accounts for 3040 % of ovarian metastatic.
Laura fiallo carvajal hospital ginecobstetrico ramon gonzalez coro. An uptodate understanding of the krukenberg tumor mechanism. Submitted papers should strictly follow the format of the sample article. Abstract krukenberg s tumor has been defined as ovarian metastasis with the presence of a signet ring cells carcinoma in an ovarian stro ma with diffuse sacomatous reaction. Krukenburg tumor is a metastatic malignancy of the ovary characterized by mucin rich signetring adenocarcinoma that primarily arises from a. Brenner tumours very rarely can occur in other locations, including the testes. The majority of patients with krukenberg tumor remain asymptomatic or have nonspecific gastrointestinal symptoms. All structured data from the file and property namespaces is available under the creative commons cc0 license. Cancer, krukenberg tumor statpearls ncbi bookshelf. Brenner tumor of the ovary is a solid, abnormal growth tumor on the ovary. This study aims to describe the unusual case of a 36yearold woman that presented to the emergency department ed with back pain and a positive urine pregnancy test. In most krukenberg tumor cases, stomach is the main primary site. Assessment revealed no intrauterine pregnancy and a small left ovarian cyst. An exceptional case of bilateral krukenberg tumor of the ovary associated with mature teratoma presented in a 54 years old patient is reported.
Credit for the recognition of this rare entity belongs to dr ibrahim ramzy 33 who first described, in 1976, the occurrence in a cellular stromal neoplasm of signet ringlike cells figure 1, e but which lacked the mucin of such cells in a krukenberg tumor or the lipid of the signet ringlike cells seen in the sclerosing stromal tumor. These tumors occur with greatest frequency in women about the age of thirtyfive. Krukenberg tumor is metastatic and it accounts for 1% to 2% of. Here we report a case of virilization associated with an extensive. Krukenberg tumor, also known as carcinoma mucocellulare, refers to the signet ring subtype of metastatic tumor to the ovary. Krukenberg tumor article about krukenberg tumor by the free. In order to analyze the clinical characteristics and prognostic factors, we retrospectively investigated 128 patients who were diagnosed with krukenberg tumor between january, 1990 and december, 2010. Krukenberg tumor krukenbergs tumor svensk definition.246 1519 135 457 1252 402 1462 1360 667 13 840 1243 155 307 999 1257 1036 1076 921 394 1450 1168 1476 167 464 402 645 625 673 53 891 177 5 1298